Treatment-related morbidity in phase III RTOG studies of extended-field irradiation for carcinoma of the prostate
Identifieur interne : 00F152 ( Main/Exploration ); précédent : 00F151; suivant : 00F153Treatment-related morbidity in phase III RTOG studies of extended-field irradiation for carcinoma of the prostate
Auteurs : M. V. Pilepich [États-Unis] ; J. Krall [États-Unis] ; F. W. George [États-Unis] ; S. O. Asbell [États-Unis] ; H. D. Plenk [États-Unis] ; R. J. Johnson [États-Unis] ; J. Stetz [États-Unis] ; M. Zinninger [États-Unis] ; B. J. Walz [États-Unis]Source :
- International Journal of Radiation Oncology, Biology, Physics [ 0360-3016 ] ; 1984.
Descripteurs français
- KwdFr :
- Adénocarcinome (radiothérapie), Attribution aléatoire, Cystite (étiologie), Diarrhée (étiologie), Essais cliniques comme sujet, Facteurs temps, Humains, Hématurie (étiologie), Lymphoedème (étiologie), Mâle, Radiothérapie (effets indésirables), Rectite (étiologie), Sténose de l'urètre (étiologie), Tumeurs de la prostate (radiothérapie).
- MESH :
- effets indésirables : Radiothérapie.
- radiothérapie : Adénocarcinome, Tumeurs de la prostate.
- étiologie : Cystite, Diarrhée, Hématurie, Lymphoedème, Rectite, Sténose de l'urètre.
- Attribution aléatoire, Essais cliniques comme sujet, Facteurs temps, Humains, Mâle.
English descriptors
- KwdEn :
- Adenocarcinoma (radiotherapy), Clinical Trials as Topic, Cystitis (etiology), Diarrhea (etiology), Hematuria (etiology), Humans, Lymphedema (etiology), Male, Proctitis (etiology), Prostatic Neoplasms (radiotherapy), Radiotherapy (adverse effects), Random Allocation, Time Factors, Urethral Stricture (etiology).
- MESH :
- adverse effects : Radiotherapy.
- etiology : Cystitis, Diarrhea, Hematuria, Lymphedema, Proctitis, Urethral Stricture.
- radiotherapy : Adenocarcinoma, Prostatic Neoplasms.
- Clinical Trials as Topic, Humans, Male, Random Allocation, Time Factors.
Abstract
The incidence, severity, time of onset, and clinical course of complications of treatment have been reviewed in the RTOG studies of extended field irradiation in carcinoma of the prostate. A total of 526 patients, entered between 1976 and 1980 and followed for a minimum of 18 months, comprised the study population. In most instances of treatment-related morbidity, the symptoms were recorded during the first several months to 1 year following completion of treatment. Late occurrences, however, were not uncommon in certain types of radiation-produced injuries, such as proctitis, hematuria, and urethral strictures. Resolution of symptoms has been observed in a large proportion of patients including those with late occurrences of treatment-related morbidity, although the probability and the pattern of resolution differed considerably from one type of morbidity to another. Symptoms of cystitis are more likely to abate than those of proctitis. In patients who develop symptoms of proctitis the probability of persistence of symptoms beyond the second year following occurrence has been estimated at 20%–30%. Hematuria and symptoms secondary to urethral strictures seem to he even more likely to recur or persist, while genital and leg edema remain chronic in the majority of patients.
Url:
DOI: 10.1016/0360-3016(84)90263-3
Affiliations:
- États-Unis
- Californie, Missouri (État), Pennsylvanie, Utah, État de New York
- Los Angeles, Saint-Louis (Missouri)
- Université de Californie du Sud, École de médecine (Université Washington de Saint-Louis)
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 003083
- to stream Istex, to step Curation: 003083
- to stream Istex, to step Checkpoint: 006042
- to stream Main, to step Merge: 010018
- to stream PubMed, to step Corpus: 006916
- to stream PubMed, to step Curation: 006916
- to stream PubMed, to step Checkpoint: 006916
- to stream Ncbi, to step Merge: 00AA34
- to stream Ncbi, to step Curation: 00AA34
- to stream Ncbi, to step Checkpoint: 00AA34
- to stream Main, to step Merge: 00FF48
- to stream Main, to step Curation: 00F152
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>Treatment-related morbidity in phase III RTOG studies of extended-field irradiation for carcinoma of the prostate</title><author><name sortKey="Pilepich, M V" sort="Pilepich, M V" uniqKey="Pilepich M" first="M. V." last="Pilepich">M. V. Pilepich</name></author><author><name sortKey="Krall, J" sort="Krall, J" uniqKey="Krall J" first="J." last="Krall">J. Krall</name></author><author><name sortKey="George, F W" sort="George, F W" uniqKey="George F" first="F. W." last="George">F. W. George</name></author><author><name sortKey="Asbell, S O" sort="Asbell, S O" uniqKey="Asbell S" first="S. O." last="Asbell">S. O. Asbell</name></author><author><name sortKey="Plenk, H D" sort="Plenk, H D" uniqKey="Plenk H" first="H. D." last="Plenk">H. D. Plenk</name></author><author><name sortKey="Johnson, R J" sort="Johnson, R J" uniqKey="Johnson R" first="R. J." last="Johnson">R. J. Johnson</name></author><author><name sortKey="Stetz, J" sort="Stetz, J" uniqKey="Stetz J" first="J." last="Stetz">J. Stetz</name></author><author><name sortKey="Zinninger, M" sort="Zinninger, M" uniqKey="Zinninger M" first="M." last="Zinninger">M. Zinninger</name></author><author><name sortKey="Walz, B J" sort="Walz, B J" uniqKey="Walz B" first="B. J." last="Walz">B. J. Walz</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:688734E8E6F7A1E016A6D3DCC3DA59C6ADD0320B</idno><date when="1984" year="1984">1984</date><idno type="doi">10.1016/0360-3016(84)90263-3</idno><idno type="url">https://api.istex.fr/document/688734E8E6F7A1E016A6D3DCC3DA59C6ADD0320B/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">003083</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">003083</idno><idno type="wicri:Area/Istex/Curation">003083</idno><idno type="wicri:Area/Istex/Checkpoint">006042</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">006042</idno><idno type="wicri:doubleKey">0360-3016:1984:Pilepich M:treatment:related:morbidity</idno><idno type="wicri:Area/Main/Merge">010018</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:6386761</idno><idno type="wicri:Area/PubMed/Corpus">006916</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">006916</idno><idno type="wicri:Area/PubMed/Curation">006916</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">006916</idno><idno type="wicri:Area/PubMed/Checkpoint">006916</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">006916</idno><idno type="wicri:Area/Ncbi/Merge">00AA34</idno><idno type="wicri:Area/Ncbi/Curation">00AA34</idno><idno type="wicri:Area/Ncbi/Checkpoint">00AA34</idno><idno type="wicri:doubleKey">0360-3016:1984:Pilepich M:treatment:related:morbidity</idno><idno type="wicri:Area/Main/Merge">00FF48</idno><idno type="wicri:Area/Main/Curation">00F152</idno><idno type="wicri:Area/Main/Exploration">00F152</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a">Treatment-related morbidity in phase III RTOG studies of extended-field irradiation for carcinoma of the prostate</title><author><name sortKey="Pilepich, M V" sort="Pilepich, M V" uniqKey="Pilepich M" first="M. V." last="Pilepich">M. V. Pilepich</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Washington University School of Medicine, St. Louis, MO.</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName></affiliation></author><author><name sortKey="Krall, J" sort="Krall, J" uniqKey="Krall J" first="J." last="Krall">J. Krall</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>RTOG Headquarters, Philadephia, PA.</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="George, F W" sort="George, F W" uniqKey="George F" first="F. W." last="George">F. W. George</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Southern California, Los Angeles, CA</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Asbell, S O" sort="Asbell, S O" uniqKey="Asbell S" first="S. O." last="Asbell">S. O. Asbell</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Albert Einstein Medical Center, Philadephia, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Plenk, H D" sort="Plenk, H D" uniqKey="Plenk H" first="H. D." last="Plenk">H. D. Plenk</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>LDS Hospital, Salt Lake City, UT</wicri:regionArea><placeName><region type="state">Utah</region></placeName></affiliation></author><author><name sortKey="Johnson, R J" sort="Johnson, R J" uniqKey="Johnson R" first="R. J." last="Johnson">R. J. Johnson</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Roswell Park Memorial Institute, Buffalo, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Stetz, J" sort="Stetz, J" uniqKey="Stetz J" first="J." last="Stetz">J. Stetz</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>RTOG Headquarters, Philadephia, PA.</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Zinninger, M" sort="Zinninger, M" uniqKey="Zinninger M" first="M." last="Zinninger">M. Zinninger</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>RTOG Headquarters, Philadephia, PA.</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Walz, B J" sort="Walz, B J" uniqKey="Walz B" first="B. J." last="Walz">B. J. Walz</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Washington University School of Medicine, St. Louis, MO.</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName></affiliation></author></analytic><monogr></monogr><series><title level="j">International Journal of Radiation Oncology, Biology, Physics</title><title level="j" type="abbrev">ROB</title><idno type="ISSN">0360-3016</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1984">1984</date><biblScope unit="volume">10</biblScope><biblScope unit="issue">10</biblScope><biblScope unit="page" from="1861">1861</biblScope><biblScope unit="page" to="1867">1867</biblScope></imprint><idno type="ISSN">0360-3016</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0360-3016</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adenocarcinoma (radiotherapy)</term><term>Clinical Trials as Topic</term><term>Cystitis (etiology)</term><term>Diarrhea (etiology)</term><term>Hematuria (etiology)</term><term>Humans</term><term>Lymphedema (etiology)</term><term>Male</term><term>Proctitis (etiology)</term><term>Prostatic Neoplasms (radiotherapy)</term><term>Radiotherapy (adverse effects)</term><term>Random Allocation</term><term>Time Factors</term><term>Urethral Stricture (etiology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adénocarcinome (radiothérapie)</term><term>Attribution aléatoire</term><term>Cystite (étiologie)</term><term>Diarrhée (étiologie)</term><term>Essais cliniques comme sujet</term><term>Facteurs temps</term><term>Humains</term><term>Hématurie (étiologie)</term><term>Lymphoedème (étiologie)</term><term>Mâle</term><term>Radiothérapie (effets indésirables)</term><term>Rectite (étiologie)</term><term>Sténose de l'urètre (étiologie)</term><term>Tumeurs de la prostate (radiothérapie)</term></keywords><keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Radiotherapy</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Radiothérapie</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Cystitis</term><term>Diarrhea</term><term>Hematuria</term><term>Lymphedema</term><term>Proctitis</term><term>Urethral Stricture</term></keywords><keywords scheme="MESH" qualifier="radiotherapy" xml:lang="en"><term>Adenocarcinoma</term><term>Prostatic Neoplasms</term></keywords><keywords scheme="MESH" qualifier="radiothérapie" xml:lang="fr"><term>Adénocarcinome</term><term>Tumeurs de la prostate</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Cystite</term><term>Diarrhée</term><term>Hématurie</term><term>Lymphoedème</term><term>Rectite</term><term>Sténose de l'urètre</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Clinical Trials as Topic</term><term>Humans</term><term>Male</term><term>Random Allocation</term><term>Time Factors</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Attribution aléatoire</term><term>Essais cliniques comme sujet</term><term>Facteurs temps</term><term>Humains</term><term>Mâle</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The incidence, severity, time of onset, and clinical course of complications of treatment have been reviewed in the RTOG studies of extended field irradiation in carcinoma of the prostate. A total of 526 patients, entered between 1976 and 1980 and followed for a minimum of 18 months, comprised the study population. In most instances of treatment-related morbidity, the symptoms were recorded during the first several months to 1 year following completion of treatment. Late occurrences, however, were not uncommon in certain types of radiation-produced injuries, such as proctitis, hematuria, and urethral strictures. Resolution of symptoms has been observed in a large proportion of patients including those with late occurrences of treatment-related morbidity, although the probability and the pattern of resolution differed considerably from one type of morbidity to another. Symptoms of cystitis are more likely to abate than those of proctitis. In patients who develop symptoms of proctitis the probability of persistence of symptoms beyond the second year following occurrence has been estimated at 20%–30%. Hematuria and symptoms secondary to urethral strictures seem to he even more likely to recur or persist, while genital and leg edema remain chronic in the majority of patients.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Californie</li><li>Missouri (État)</li><li>Pennsylvanie</li><li>Utah</li><li>État de New York</li></region><settlement><li>Los Angeles</li><li>Saint-Louis (Missouri)</li></settlement><orgName><li>Université de Californie du Sud</li><li>École de médecine (Université Washington de Saint-Louis)</li></orgName></list><tree><country name="États-Unis"><region name="Missouri (État)"><name sortKey="Pilepich, M V" sort="Pilepich, M V" uniqKey="Pilepich M" first="M. V." last="Pilepich">M. V. Pilepich</name></region><name sortKey="Asbell, S O" sort="Asbell, S O" uniqKey="Asbell S" first="S. O." last="Asbell">S. O. Asbell</name><name sortKey="George, F W" sort="George, F W" uniqKey="George F" first="F. W." last="George">F. W. George</name><name sortKey="Johnson, R J" sort="Johnson, R J" uniqKey="Johnson R" first="R. J." last="Johnson">R. J. Johnson</name><name sortKey="Krall, J" sort="Krall, J" uniqKey="Krall J" first="J." last="Krall">J. Krall</name><name sortKey="Plenk, H D" sort="Plenk, H D" uniqKey="Plenk H" first="H. D." last="Plenk">H. D. Plenk</name><name sortKey="Stetz, J" sort="Stetz, J" uniqKey="Stetz J" first="J." last="Stetz">J. Stetz</name><name sortKey="Walz, B J" sort="Walz, B J" uniqKey="Walz B" first="B. J." last="Walz">B. J. Walz</name><name sortKey="Zinninger, M" sort="Zinninger, M" uniqKey="Zinninger M" first="M." last="Zinninger">M. Zinninger</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 00F152 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 00F152 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:688734E8E6F7A1E016A6D3DCC3DA59C6ADD0320B
|texte= Treatment-related morbidity in phase III RTOG studies of extended-field irradiation for carcinoma of the prostate
}}
| This area was generated with Dilib version V0.6.31. |  |